1. Vol 13, No 8 (August 31, 2024) - Translational Lung Cancer Research
31 aug 2024 · Effect of family history of cancer on postoperative survival in patients with non-small cell lung cancer ... Lin Xu, Wenjie Xia, Rong Yin, Ninglei ...
Translational Lung Cancer Research provides practical up-to-date information on prevention, early detection, diagnosis, and treatment of lung cancer.
2. A study protocol for HEalth-Related quality of life-intervention in ... - Trials
4 nov 2020 · This clinical trial aims to evaluate the efficacy and safety of XBYRT in improving CRF and quality of life (QOL) of cancer survivors.
Cancer-related fatigue (CRF) is a debilitating condition which commonly affects cancer survivors. The management of CRF remains a challenge due to the lack of effective pharmacological interventions. Traditional Chinese medicine (TCM) could be a potential therapeutic option for CRF. The modified Xiang Bei Yang Rong Tang (XBYRT) is a TCM herbal decoction, formulated to improve fatigue symptoms in cancer survivors. This clinical trial aims to evaluate the efficacy and safety of XBYRT in improving CRF and quality of life (QOL) of cancer survivors. This is a single centre, randomized, double-blind, placebo-controlled, parallel trial. Eighty cancer survivors will be recruited and randomized to receive the XBYRT or placebo decoction, in a ratio of 1:1. Participants will consume the XBYRT/placebo decoction daily for 8 weeks and undergo assessments at baseline and 4, 8 and 10 weeks after baseline. The participants will be assessed for patient-reported outcomes (PRO), blood biomarkers and adverse events at each time point. The primary outcome is the overall health and QOL status, at 8 weeks follow-up. The secondary outcomes are the effects of XBYRT on fatigue levels, cancer-related cognitive impairment and QOL, as assessed by PRO. The incidence of adverse events and the effects of the XBYRT decoction on blood biomarkers associated with CRF will also be evaluated. Efficacy and safety outcomes from this trial will provide important clinical data to guide future large-scale randomized co...
3. Yunfei Yuan | Liver Surgery - Sun Yat-sen University Cancer Center
He is the pioneer in China to evaluate the hepatic functional reserve for patients with hepatocellular carcinoma with one parameter, retention rate of ...
sun yat-sen university cancer center,Sun Yat-sen University Cancer Center,SYSUCC
4. Yoon Jung Chang - Cancer Research and Treatment
Satisfaction with and perceived benefits of needs-assessment related to rehabilitation after chemotherapy among patients with breast cancer
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5. Chinese Journal of Cancer: Cancer Conmmunications
This thematic series discusses the molecular classifications of gastric cancer by the Cancer Genome Atlas (TCGA) and the Asian Cancer Research Group (ACRG) as ...
Cancer Communications(Chinese Journal of Cancer© is indexed in SCI and PubMed. The CJC publishes original research, reviews, perspectives, supplements, and spotlights in all areas of cancer research.
6. A Prognostic Model Based on Nutritional Indexes for Patients with ...
Shen-Li Jiang; Ming-Cong Chen; Guang-Xian You; Rong-Biao Ying; Zhi-Rui Zhou ... with a Recent Diagnosis of Cancer Are at Higher Risk. J Nutr Health Aging ...
Abstract Background We aimed to identify the nutritional indexes, construct a prognostic model, and develop a nomogram for predicting individual survival probability in pan-cancers. Methods We collected nutritional indicators, clinicopathological characteristics, and previous major treatment details of the patients. The enrolled patients were randomly divided into training and validation cohorts. Lasso regression cross-validation was used to determine the variables to include in the cox regr…
7. Xie Chuanmiao | Medical Imaging - Sun Yat-sen University Cancer Center
Currently, he serves as the director for the Department of Imaging at the Sun Yat-sen University Cancer Center, Chief Physician and Doctoral Advisor. He has ...
sun yat-sen university cancer center,Sun Yat-sen University Cancer Center,SYSUCC
8. [PDF] 中 医 肿 瘤 治 疗 - Maciocia Online
Yin and Jing. This has both a Chinese and a Western aspect. From the point of view of Chinese medicine, when cancer manifests with masses, there ...
9. Vol 11, No 4 (April 29, 2022) - Translational Lung Cancer Research
29 apr 2022 · Rui Fu, Jia-Tao Zhang, Rong-Rong Chen, Hong Li, Zai-Xian Tai, Hao-Xiang Lin, Jian Su, Xiang-Peng Chu, Chao Zhang, Zhen-Bin Qiu, Zi-Hao Chen, ...
Translational Lung Cancer Research provides practical up-to-date information on prevention, early detection, diagnosis, and treatment of lung cancer.
10. Chinese Journal of Cancer Research: Home
Chinese Journal of Cancer Research (CJCR) is published by AME Publishing Company (www.amepc.org) in association with Chinese Anti-Cancer Association.
Chinese Journal of Cancer Research (CJCR) is published by AME Publishing Company (www.amepc.org) in association with Chinese Anti-Cancer Association. CJCR is a bi-monthly peer-reviewed journal in English, and is an international journal devoted to the life sciences and medical sciences.
11. Yoon Jung Choi - Cancer Research and Treatment
Overexpression of circulating CD38+ NK cells in colorectal cancer was associated with lymph node metastasis and poor prognosis ... Ying Duan, Hangrong Fang ...
12. Granzyme B PET Imaging of Combined Chemotherapy and ...
... with immune checkpoint inhibitor (ICI) monotherapy in cancer patients. In ... Results: [18F]AlF-mNOTA-GZP tumor uptake was able to clearly ...
Purpose: Chemotherapeutic adjuvants, such as oxaliplatin (OXA) and 5-fluorouracil (5-FU), that enhance the immune system, are being assessed as strategies to improve durable response rates when used in combination with immune checkpoint inhibitor (ICI) monotherapy in cancer patients. In this study, we explored granzyme B (GZB), released by tumor-associated immune cells, as a PET imaging-based stratification marker for successful combination therapy using a fluorine-18 (18F)-labelled GZB peptide ([18F]AlF-mNOTA-GZP). Methods: Using the immunocompetent CT26 syngeneic mouse model of colon cancer, we assessed the potential for [18F]AlF-mNOTA-GZP to stratify OXA/5-FU and ICI combination therapy response via GZB PET. In vivo tumor uptake of [18F]AlF-mNOTA-GZP in different treatment arms was quantified by PET, and linked to differences in tumor-associated immune cell populations defined by using multicolour flow cytometry. Results: [18F]AlF-mNOTA-GZP tumor uptake was able to clearly differentiate treatment responders from non-responders when stratified based on changes in tumor volume. Furthermore, [18F]AlF-mNOTA-GZP showed positive associations with changes in tumor-associated lymphocytes expressing GZB, namely GZB+ CD8+ T cells and GZB+ NK+ cells. Conclusions: [18F]AlF-mNOTA-GZP tumor uptake, driven by changes in immune cell populations expressing GZB, is able to stratify tumor response to chemotherapeutics combined with ICIs. Our results show that, while the immunomodulatory mode...
13. A Retrospective, Population-Based Cohort Study In China
4 jun 2024 · Development and Validation of a Machine Learning Model for Predicting the Prognosis of Older Patients with Gastric Cancer: A Retrospective, ...
Background: Despite numerous prognostic models for gastric cancer, there remains a gap in accurate prognostic tools tailored for older patients aged 75 yea
14. Combination therapy with micellarized cyclopamine and temozolomide ...
27 jun 2017 · https://doi.org/10.18632/oncotarget.17205 Yu-Jie Liu, Ying-Cong Ma, Wen-Jie Zhang, Zhen-Zhen Yang, De-Sheng Liang, Zhi-Fu Wu, Xian-Rong Qi.
// Yu-Jie Liu 1 , Ying-Cong Ma 1 , Wen-Jie Zhang 1 , Zhen-Zhen Yang 1 , De-Sheng Liang 1 , Zhi-Fu Wu 2 and Xian-Rong Qi 1 1 Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery System, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, PR China 2 School of Materials Science and Engineering, Baise University, Guangxi Baise, 533000, PR China Correspondence to: Xian-Rong Qi, email: qixr@bjmu.edu.cn Keywords: cyclopamine, temozolomide, hedgehog pathway, synergistic effect, glioma Received: January 28, 2017 Accepted: April 03, 2017 Published: April 18, 2017 ABSTRACT Glioblastoma multiforme (GBM) is the most common and deadly brain cancer, characterized by its aggressive proliferation to adjacent tissue and high recurrence rate. We studied the efficacy and related mechanisms of the combination of cyclopamine (Cyp, a Sonic-hedgehog pathway (Shh) inhibitor) and temozolomide (TMZ, the clinically most used chemotherapeutic agent) in anti-GBM treatment. The micellarized Cyp (MCyp) showed better performance than Cyp solution in inhibiting GBM cells proliferation (3.77-fold against U87 MG cells and 3.28-fold against DBTRG-05MG cells) and clonogenity (1.35-fold against U87 MG cells and 2.17-fold against DBTRG-05MG cells), and preferred behavior of inhibiting cell invasion, colony formation through attenuated Gli1 expression. In addition, combination of MCyp...
15. Medical expenditure for lung cancer in China: a multicenter, hospital ...
17 aug 2021 · Lung cancer is the most prevalent cancer, and the leading cause of cancer-related deaths in China. The aim of this study was to estimate the ...
Lung cancer is the most prevalent cancer, and the leading cause of cancer-related deaths in China. The aim of this study was to estimate the direct medical expenditure incurred for lung cancer care and analyze the trend therein for the period 2002–2011 using nationally representative data in China This study was based on 10-year, multicenter retrospective expenditure data collected from hospital records, covering 15,437 lung cancer patients from 13 provinces diagnosed during the period 2002–2011. All expenditure data were adjusted to 2011 to eliminate the effects of inflation using China’s annual consumer price index. The direct medical expenditure for lung cancer care (in 2011) was 39,015 CNY (US$6,041) per case, with an annual growth rate of 7.55% from 2002 to 2011. Drug costs were the highest proportionally in the total medical expenditure (54.27%), followed by treatment expenditure (14.32%) and surgical expenditure (8.10%). Medical expenditures for the disease varied based on region, hospital level, type, and stage. The medical expenditure for lung cancer care is substantial in China. Drug costs and laboratory test are the main factors increasing medical costs.
16. About - CHANGPINGLABORATORY Leading Scientists
Academician Dongxin Lin has been focusing on reseach in cancer genetics and genomics to provide evidences for translational and precision medicine.
Changping Laboratory is one of China's new type of R&D (Research & Development) institutions with its vision to establish a world-class hub for science, technology and innovation (STI) in life science.
17. American Journal of Cancer Research - e-Century Publishing Corporation
American Journal of Cancer Research (with official SCI Impact Factor 3.600) is an open access, peer reviewed online journal for oncology including clinical ...
American Journal of Cancer Research (with official SCI Impact Factor 3.600) is an open access, peer reviewed online journal for oncology including clinical oncology and experimental cancer research.
18. World Journal of Radiology - Baishideng Publishing Group
Wu Size, Tu Rong, Liang Xian. Patchy echogenicity of the liver in patients with chronic hepatitis B does not indicate poorer elasticity. Ultrasonography ...
19. Search Results | New Medicine - 医学新知
... Ying-Hui JIN Xiao-Dong LI Xian-Tao ZENG · Transurethral plasmakinetic ... Prostate cancer Incidence Mortality Burden of disease Disability-adjusted life years ...
New Medicine is a comprehensive medical academic journal approved by the General Administration of Press and Publication of The People's Republic of China, supervised by hubei Provincial Party Committee of Chinese Agricultural and Industrial Demo
20. A Chinese Decoction, Kuan-Sin-Yin, Improves Autonomic Function and ...
Chinese medicine (TCM) decoction, which has been shown to have cytostatic effects on cancer cells and involved in the TCM theory of promoting yin-yang ...
The safety and effectiveness of KSY in improving AD in mCRC patients are through regulating the vagal-sympathetic dynamic balance, which correspond to the TCM yin-yang concept of energy. Background Kuan-Sin-Yin (KSY) is a traditional Chinese medicine (TCM) decoction, which has been shown to have cytostatic effects on cancer cells and involved in the TCM theory of promoting yin-yang balance.Sonce many cancer patients suffer from autonomic dysfunction (AD), which correspond to yin-yang imbalance in TCM. The aim of this study is to evaluate the possible effect of KSY in metastatic colon cancer (mCRC) patients with AD. Methods We conducted a single-group experiment. Total 52 qualified patients were enrolled. Participants took the KSY daily for 2 weeks. The primary outcome was KSY efficacy as reflected in the heart rate variability (HRV) and electrical conductivity (µA) over 12 meridian points. Autonomic function was examined before and after the KSY intervention. The vagal and sympathetic tone were recorded by HRV; 12 meridian energies were measured using a meridian energy analysis device. Secondary outcomes were cancer-related symptoms and patient quality of life (QoL). Results The results showed that the KSY intervention improved AD via increasing the vagal tone (HF: P = .041), but not the sympathetic tone (LF: P = .154); total autonomic activity was significantly enhanced (HRV activity: P = .013). Intriguingly, energy increased more over the yin meridian (P = .010) than over t...
